1074-97-1

Basic information

• Product Name: 4,6-Dihydroxypyrimidine-5-carboxamide
• Synonyms: 4,6-Dihydroxypyrimidine-5-carboxamide;2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carboxaMide;2,4-dihydroxypyrimidine-5-carboxamide
• CAS NO: 1074-97-1
• Molecular Formula: C₅H₅N₃O₃
• Molecular Weight: 155.11
• Mol File: 1074-97-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,6-Dihydroxypyrimidine-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dihydroxypyrimidine-5-carboxamide(1074-97-1)
• EPA Substance Registry System: 4,6-Dihydroxypyrimidine-5-carboxamide(1074-97-1)

Safety Data

• Hazardous Substances Data: 1074-97-1(Hazardous Substances Data)

Usage

Uses

2,4-Dihydroxypyrimidine-5-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.

Upstream product

• 42821-92-1 methyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 65696-20-0 methyl ureidomethylenemalonate 

Downstream Products

• 66-22-8 uracil 

Relevant articles and documents

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Studies on fluorinated pyrimidines. I. A new method of synthesizing 5-fluorouracil and its derivatives

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