107401-57-0Relevant academic research and scientific papers
Samarium Barbier reactions of α-iodomethyloxazoles and thiazoles with aliphatic aldehydes
Williams, David R.,Berliner, Martin A.,Stroup, Bryan W.,Nag, Partha P.,Clark, Michael P.
, p. 4099 - 4102 (2007/10/03)
(Chemical Equation Presented) The reductive coupling of substituted α-iodomethyloxazoles and thiazoles with aliphatic aldehydes under Barbier conditions provides an effective method for the direct incorporation of intact heterocyclic systems.
Samarium diiodide mediated barbier-type reaction of 2-chloromethylbenzoxazole and 2-chloromethylbenzothiazole with carbonyl compounds: A convenient synthesis of 1-(β-hydroxyalkyl)benzoxazoles and 1-(β-hydroxyalkyl)benzothiazoles
Xu, Xiaoliang,Zhang, Yongmin
, p. 3551 - 3559 (2007/10/03)
1-(β-Hydroxyalkyl)benzoxazoles and 1-(β -hydroxyalkyl)benzothiazoles were prepared via reductive addition reactions of 2-chloromethylbenzoxazole and 2-chloromethylbenzothiazole with carbonyl compounds under mild conditions mediated by SmI2.
General Method for an Aldol-Type Reaction of 2-Methylbenzothiazole with Carbonyl Compounds
Chikashita, Hidenori,Ikegami, Seiji,Okumura, Takeshi,Itoh, Kazuyoshi
, p. 375 - 377 (2007/10/02)
A general and versatile method for the preparation of a variety of β-hydroxybenzothiazoles (aldol-type adducts) by the reaction of α-lithio-2-methylbenzothiazole with carbonyl compounds was proposed.As an example of the use of α-lithio-2-methylbenzothiazo
