107401-71-8Relevant academic research and scientific papers
One-pot sequential multicomponent route to 2,4-diaminothiazoles - A facile approach to bioactive agents for cancer therapeutics
Sreejalekshmi, Kumaran G.,Rajasekharan, Kallikat N.
, p. 3627 - 3629 (2012/09/22)
A facile one-pot sequential three-component route to 2,4-diaminothiazoles is reported. The new approach employs the mildest reaction conditions and commercially available reagents to generate diverse 2-alkyl/arylamino-4-amino-5- aroyl/heteroylthiazoles in short reaction times, good yield, and purity.
Studies on the Synthesis of 5-Acyl-2,4-diaminothiazoles from Amidinothioureas
Rajasekharan, K. N.,Nair, K. P.,Jenardanan, G. C.
, p. 353 - 355 (2007/10/02)
1-Alkyl or aryl-3-amidinothioureas with or without substituents on the amidino moiety react with α-haloketones to yield 5-acyl-2,4-diaminothiazoles.
