34678-06-3

Upstream product

• 113-00-8 guanidine nitrate 
• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 107401-73-0 (4-amino-2-p-tolylaminothiazol-5-yl)(4-bromophenyl)methanone 
• 107401-71-8 4-amino-5-(p-methylbenzoyl)-2-(p-methylphenylamino)thiazole 
• 107401-68-3 (4-amino-2-p-tolylamino-thiazol-5-yl)-phenyl-methanone 

Relevant academic research and scientific papers

NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF

The present invention discloses a novel EGFR inhibitor compound of formula (1), process for preparation thereof and methods of treating abnormal cell growth in mammals by administering the compounds of formula (1). wherein, R is selected from hydrogen, alkyl, nitro, halogens such as chlorine, bromine, fluorine and iodine; Rl= hydrogen, alkyl, alkoxy, aryl, nitro, halogens such as chlorine, bromine, fluorine and iodine, trifluoromethyl, thioalkyl, trifluromethoxy, trialkylsilyl.

Studies in the antimicrobial activities of 1-substituted-3-formamidinothio- carbamides and 1,3-bis-(substitutedthioamido)guanidines

The present research work has been undertaken in the synthesis of nitrogen, nitrogen and sulphur containing heteroacycles and heterocycles and to investigate their applications in medicinal, agricultural, industrial, pharmacological and biochemical facult