107433-64-7Relevant academic research and scientific papers
The Synthesis of Aromatic Leukotriene Analogues; Regioselective Trapping of 2,4'-Dilithiophenylethyne
Furber, Mark,Taylor, Richard J. K.,Burford, S. Cliff
, p. 1573 - 1578 (2007/10/02)
The 8,11-bridged aromatic leukotriene B4 analogues (3), (4), and (5), in which conformational freedom is restricted, have been prepared by extremely short synthetic routes.Conditions are described which allow the regioselective electrophillic t
AN IMPROVED PROCEDURE FOR THE GENERATION AND SELECTIVE TRAPPING OF 2,4'-DILITHIOPHENYLETHYNE
Furber, Mark,Taylor, Richard J. K.,Burford, S. Cliff
, p. C35 - C38 (2007/10/02)
2,4'-Dilithiophenylethyne, prepared by treatment of 4-bromophenylethyne with two equivalents of butyllithium, reacts selectively with electrophilic reagents at the 4'-position provided the correct temperature and solvent combination are employed.The successive addition of two different electrophiles gives the 2,4'-dialkylated product in a regioselective manner.
