107433-65-8

Upstream product

• 6026-86-4 methyl 4-formylbutanoate 
• 107433-64-7 1-(4-ethynylphenyl)nonan-1-ol 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 124-19-6 nonan-1-al 

Downstream Products

• 113331-94-5 (Z)-methyl 5-hydroxy-7-<4-(1-hydroxynonyl)phenyl>hept-6-enoate 
• 113331-96-7 (Z)-6-<4-(1-hydroxynonyl)styryl>tetrahydropyran-2-one 
• 113331-95-6 (Z)-5-hydroxy-7-<4-(1-hydroxynonyl)phenyl>hept-6-enoic acid 

Relevant academic research and scientific papers

PHENYLENE, FURYL, AND THIENYL LEUKOTRIENE B4 ANALOGUES

This invention relates to leukotriene B 4 antagonists having the structure STR1 and the pharmaceutically acceptable addition salts thereof; wherein R 1 is lower alkyl having 1-10 carbon atoms; or lower alkenyl or alkynyl having 2-10 carbon atoms; or lower

The Synthesis of Aromatic Leukotriene Analogues; Regioselective Trapping of 2,4'-Dilithiophenylethyne

The 8,11-bridged aromatic leukotriene B4 analogues (3), (4), and (5), in which conformational freedom is restricted, have been prepared by extremely short synthetic routes.Conditions are described which allow the regioselective electrophillic t

AN IMPROVED PROCEDURE FOR THE GENERATION AND SELECTIVE TRAPPING OF 2,4'-DILITHIOPHENYLETHYNE

2,4'-Dilithiophenylethyne, prepared by treatment of 4-bromophenylethyne with two equivalents of butyllithium, reacts selectively with electrophilic reagents at the 4'-position provided the correct temperature and solvent combination are employed.The successive addition of two different electrophiles gives the 2,4'-dialkylated product in a regioselective manner.