107441-56-5Relevant academic research and scientific papers
A new diastereoselective synthesis of a 1β-methylcarbapenem intermediate
Oh, Chang-Young,Ham, Won-Hun
, p. 2365 - 2366 (2007/10/03)
A 1β-methylcarbapenem key intermediate is synthesized from methyl (R)- 3-hydroxybutyrate via the diastereoselective alkylation and regioselective cuprate ring opening of a chiral epoxide which is readily prepared from Sharpless asymmetric epoxidation of the corresponding allylic alcohol.
3-Acyltetramic Acid Antibiotics. 3. An Approach to the Synthesis of Bu-2313
Ireland, Robert E.,Wardle, Robert B.
, p. 1780 - 1789 (2007/10/02)
An approach to the synthesis of the bicyclononane portion of the 3-acyltetramic acid antibiotic Bu-2313 is presented.The highly unstable α-keto aldehyde obtained by Swern oxidation of the diol 23 was allowed to condense with the unreactive α-keto phosphor
