107451-16-1

Upstream product

• 111-25-1 1-bromo-hexane 
• 2867-47-2 2-(dimethylamino)ethyl methacrylate 
• 4385-04-0 N,N-dimethylhexylamine 
• 4513-56-8 2-bromoethyl methacrylate 

Relevant academic research and scientific papers

Construction of a quaternary ammonium salt platform with different alkyl groups for antibacterial and biosensor applications

An electrochemical platform was designed using biocompatible quaternary ammonium salts containing alkyl groups with different chain lengths as electrode materials for visible protein immobilization on a glassy carbon (GC) electrode. The electrode was constructed using a simple self-assembly method relying on the electrostatic interaction between negatively charged hemoglobin (Hb) and positively charged quaternary ammonium materials. The Hb/quaternary ammonium salts/GC assembly exhibited excellent catalytic and electrochemical activities. Additionally, the structure-function properties of the quaternary ammonium salts on the electrochemical behavior of Hb was systematically investigated for various alkyl chain lengths between monomer and polymeric structures. Meanwhile, the corresponding bactericidal activities of the monomers and related polymers were evaluated by determining the minimum bactericidal concentration (MBC), minimum inhibitory concentration (MIC), and inhibitory zone diameters against bacteria. The results of these studies demonstrated that the quaternary ammonium monomers not only immobilized more proteins, but also displayed better antibacterial activity as alkyl chain length increased. Moreover, polymers possessed higher antimicrobial activities than their monomeric counterparts. However, the efficiency of the direct electron transfer process and the antibacterial properties of long-chain polymers were limited because they were prone to aggregation and blistering. In summary, the present results provide convenient access to direct electrochemistry using an immobilized redox protein. Furthermore, the potential to use the obtained materials in the construction of third-generation electrochemical biosensors was evaluated.

Acrylate functionalized tetraalkylammonium salts with ionic liquid properties

Acrylate functionalized ionic liquids based on tetraalkylammonium salts with terminal acrylates- and methylacrylates were synthesized. Melting points and ionic conductivity of twenty compounds in six groups were determined. Within one group the effect of three different counterions was investigated and discussed. The groups differ in cationic structure elements because of their functional groups such as acrylate and methacrylate, alkyl residues at the nitrogen and number of quaternary ammonium atoms within the organic cation. The effect of these cationic structure elements has been examined concerning the compiled parameters with a view to qualifying them as components for solid state electrolytes. The newly synthesized ionic liquids were characterized by NMR and FTIR analysis. The exchange of halide ions like bromide as counter ions to weakly coordinating [PF6]-, [OTf]- or [TFSI]- reduces the melting points significantly and leads to an ion conductivity of about 10-4 S/cm at room temperature. In the case of the dicationic ionic liquid, an ion conductivity of about 10-3 S/cm was observed.

Antimicrobial adhesive films

A multi-layer film for reducing microbial contamination on a surface. The multi-layer film can include a core layer having a first surface and a second surface opposite the first surface, an adhesive layer disposed adjacent the first surface of the core layer, and an antimicrobial layer disposed adjacent the second surface. The antimicrobial layer can include a cross-linked matrix and an antimicrobial agent dispersed within the cross-linked matrix, where the cross-linked matrix is derived from a polymerizable precursor comprising a material selected from the group consisting of a polymerizable monomer, a polymerizable polymer having a molecular weight of about 1,000 or less, and combinations thereof.

ANTIBACTERIAL MONOMERS, ANTIBACTERIAL RESINS AND DENTAL COMPOSITES COMPRISING THE ANTIBACTERIAL RESINS

Provided herein are antibacterial monomers, antibacterial resins comprising a resin and the monomers, and dental composites comprising the antibacterial resins and a filler, and methods of making the same. The dental composite can optionally contain amorphous calcium phosphate nanoparticles. The dental composites display strongly antibacterial properties, increased calcium and phosphate ion release, and improved mechanical properties.

METHODS, DEVICES AND SYSTEMS FOR BIOCIDAL SURFACE ACTIVITY

A method of applying a biocidal polymer to a surface including applying a solution of the biocidal polymer to the surface, wherein the biocidal polymer includes biocidal groups and the biocidal polymer is insoluble in water. The biocidal groups can be selected from the group consisting of quaternary salt groups or haloamino groups.