107462-36-2Relevant academic research and scientific papers
A convergent approach to cyclopeptide alkaloids: Total synthesis of sanjoinine G1
Temal-Laib, Taoues,Chastanet, Jacqueline,Zhu, Jieping
, p. 583 - 590 (2007/10/03)
A general strategy for the synthesis of cyclopeptide alkaloids containing an endocyclic aryl-alkyl ether bond has been developed featuring a key intramolecular SNAr reaction. The importance of the N-terminal protective group in the realization
An asymmetric total synthesis of sanjoinine G1
Laib, Taoues,Zhu, Jieping
, p. 83 - 86 (2007/10/03)
A convergent total synthesis of sanjoinine G1, a 14-membered cyclopeptide alkaloid was described. Formation of aryl-alkyl ether bond with concomitant construction of macrocycle by way of an intramolecular SNAr reaction was the key step in this synthesis.
Total synthesis of the cyclopeptide alkaloid sanjoinine G1 and its C-11 epimer
East, Stephen P.,Shao, Feng,Williams, Lorenzo,Joullie, Madeleine M.
, p. 13371 - 13390 (2007/10/03)
The naturally occurring cyclopeptide alkaloid sanjoinine G1 and its C- 11 epimer were synthesized in 18 steps from D-serine. The key steps in the synthesis were the formation of the alkylaryl ether linkage via an S(N)Ar reaction with 4-fluorobenzonitrile
Total Synthesis of Sanjoinine-G1
Han, Byung Hoon,Kim, Yong Chul,Park, Man Ki,Park, Jeong Hill,Go, Hyun Jung,at al.
, p. 1909 - 1914 (2007/10/02)
Sanjoinine-G1 (1), a 14-membered cyclopeptide, was synthesized with stereoselective reactions.Started from D-serine, a cyclic precursor for various frangulanine type 14-membered cyclopeptide alkaloids was synthesized and the side chain acylation product was identical with the natural sanjonine-G1 (17 steps, overall yield 1.36percent).
