107463-56-9Relevant academic research and scientific papers
Design, synthesis, molecular prediction and biological evaluation of pyrazole-azomethine conjugates as antimicrobial agents
Mukhtar, Shorouk S.,Hassan, Ashraf S.,Morsy, Nesrin M.,Hafez, Taghrid S.,Saleh, Fatma M.,Hassaneen, Hamdi M.
, p. 1564 - 1580 (2021)
A series of Schiff bases linked with heterocyclic moiety (6a–c, 7a–c, 11a–c, 12a–c, and 13a–c) and ferrocenyl Schiff bases (15a–c) were designed, synthesized, and confirmed based on the spectral data. Also, evaluations of their in?vitro antibacterial and
Potassium 2-cyanoethylene-1-thiolate derivatives: A new preparative route to 2-cyanoketene S,N-acetals and pyrazole derivatives
Elgemeie, Galal H.,Elghandour, Ahmed H.,Abd Elaziz, Ghada W.
, p. 3281 - 3291 (2004)
The novel ketene S,N-acetals 4a-e were readily prepared by the reaction of substituted cyanoacetanilides with phenylisothiocyanate in the presence of potassium hydroxide, followed by alkylation of the produced salts with methyl iodide. The reaction of compounds 4 with hydrazines afforded different substituted pyrazoles.
Design, synthesis and antibacterial activity of N-aryl-3-(arylamino)-5-(((5-substituted furan-2-yl)methylene)amino)-1H-pyrazole-4-carboxamide as nitrofurantoin analogues
Hassan, Ashraf S.,Moustafa, Gaber O.,Morsy, Nesrin M.,Abdou, Amr M.,Hafez, Taghrid S.
, p. 4469 - 4481 (2020/12/09)
Nitrofurantoin is an effective drug and used for treating urinary infectious diseases. A series of nitrofurantoin analogues bearing furan and pyrazole scaffolds as N-aryl-3-(arylamino)-5-(((5-substituted furan-2-yl)methylene)amino)-1
V2O5/SiO2 as an efficient catalyst in the synthesis of 5-amino-pyrazole derivatives under solvent free condition
Khatab, Tamer K.,Hassan, Ashraf S.,Hafez, Taghrid S.
, p. 135 - 142 (2019/03/21)
An efficient and facile approach for the synthesis of 5-aminopyrazoles from ketene S,N-acetal and hydrazine hydrate via catalytic reaction under solvent free condition has been described. V2O5/SiO2 as a heterogeneous catalyst was prepared and characterize
A direct route to a new class of acrylamide thioglycosides
Elgemeie, Galal H.,Zaghary, Wafaa A.,Amin, Kamelia M.,Nasr, Tamer M.
, p. 373 - 378 (2008/12/21)
The preparation of a new class of acrylamide thioglycosides via one-pot reaction of the potassium 2-cyanoethylene-1-thiolate salts with 2,3,4,6-tetra-O-acetyl-α-D-gluco- and galactopyranosyl bromides has been studied. The E-configuration of these thioglycosides was proven by their transformations to the corresponding 5-aminopyrazoles. Copyright Taylor & Francis Group, LLC.
