107468-09-7

Basic information

• Product Name: 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, methyl ester, (Z)-
• CAS NO: 107468-09-7
• Molecular Formula: C11H9F3O2
• Molecular Weight: 230.186
• Mol File: 107468-09-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, methyl ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, methyl ester, (Z)-(107468-09-7)
• EPA Substance Registry System: 2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-, methyl ester, (Z)-(107468-09-7)

Safety Data

• Hazardous Substances Data: 107468-09-7(Hazardous Substances Data)

Upstream product

• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 21906-39-8 3-(trifluoromethyl)phenylacetone 
• 124-41-4 sodium methylate 
• 107468-13-3 1,3-Dibromo-1-(3-trifluoromethyl-phenyl)-propan-2-one 

Relevant articles and documents

Diastereoselective method of preparing olefins by means of the horner-wadsworthemmons reaction, comprising the addition of a tris-(polyoxaalkyl)-amine sequestering agent

The invention relates to a process for the diastereoselective preparation of olefins via the Homer-Wadsworth-Emmons reaction, which consists in reacting at low temperature a phosphonate with a carbonyl derivative in the presence of a base in a suitable solvent, characterized in that a tris(polyoxaalkyl)amine sequestering reagent of formula (I): N—[CHR1—CHR2—O—(CHR3—CHR4—O)n—R5]3 (I), wherein: n is an integer between 0 and 10; R1, R2, R3 and R4 may be identical or different, and represent a hydrogen atom or an alkyl radical containing from 1 to 4 carbon atoms; R5 represents a hydrogen atom, an alkyl or cycloalkyl radical containing up to 12 carbon atoms, a phenyl radical or a radical of formula —CμH2μ-Φ, or CmH2m+1-Φ-, with m being an integer between 1 and 12 and Φ being a phenyl radical; is added in an amount that is sufficient to increase the diastereoselectivity of the olefin.

STEREOSELECTIVE PREPARATION OF METHYL (Z)-CINNAMATES BY FAVORSKII REARRANGEMENT

1,3-Dibromo-1-phenylacetones, readily prepared by direct bromination of the parent phenylacetone, react with methanolic sodium methoxide to yield stereoselectively methyl (Z) cinnamates in good yield.