1075256-87-9

Basic information

• Product Name: 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one
• Synonyms: 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one
• CAS NO: 1075256-87-9
• Molecular Weight: 440.769
• Mol File: 1075256-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one(1075256-87-9)
• EPA Substance Registry System: 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one(1075256-87-9)

Safety Data

• Hazardous Substances Data: 1075256-87-9(Hazardous Substances Data)

Upstream product

• 39644-80-9 β-(4-bromobenzoyl)acrylic acid 
• 1197-56-4 ammonium (4-chlorophenyl)carbamodithioate 

Downstream Products

• 1075256-95-9 2,4-bis[2-(4-bromophenyl)-2-oxoethylidene]cyclobutane-1,3-dione 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 4999-62-6 1-chloro-4-[(cyanocarbonothioyl)amino]benzene 
• 1075256-91-5 (5E)-5-[2-(4-bromophenyl)-2-oxoethylidene]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one 
• 1075256-90-4 (5Z)-5-[2-(4-bromophenyl)-2-oxoethylidene]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one 

Relevant articles and documents

Studies on 4-thiazolidinones: Scope of the reactions of 3-aryl-2-thioxo-1,3-thiazolidin-4-ones with cyanide and cyanate ions

Treatment of 3-aryl-2-thioxo-1,3-thiazolidin-4-ones 1 with CN- and NCO- effected the ring cleavage providing [(cyanocarbonothioyl) amino]benzenes 4 and arylisothiocyanates 5, respectively. Similar treatment of 5-(2-aryl-2-oxoethyl) derivatives 2 afforded 2,4-bis(2-aryl-2-oxoethylidene) cyclobutane-1,3-diones 6 along with each of the preceding products. Treatment of the respective (E,Z)-5-(2-aryl-2-oxoethylidene) analogues 3b and 3c with CN- gave 4b and 4c and 2-(arylcarbonyl)-2-methoxy-4- oxopentanedinitriles 7b and 7c, in addition to 3,6-bis[2-(4-chlorophenyl)-1- methoxy-2-oxoethylidene]-1,4-dithiane-2,5-dione 8c, which has been generated from 3c. Reactions of 3c or 3d with NCO- provided 5c or 5d, together with 8c or 8d as pure isomers. In the formation of the MeO products 7 and 8, the solvent (MeOH) has participated. Structures of these products are based on microanalytical and spectroscopic data. Rationalizations for the above transformations are given.