4999-62-6

Basic information

• Product Name: N-(4-Chlorophenyl)-1-cyanothioformamide
• Synonyms: N-(4-Chlorophenyl)-1-cyanothioformamide
• CAS NO: 4999-62-6
• Molecular Formula: C₈H₅ClN₂S
• Molecular Weight: 196.66
• Mol File: 4999-62-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-Chlorophenyl)-1-cyanothioformamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Chlorophenyl)-1-cyanothioformamide(4999-62-6)
• EPA Substance Registry System: N-(4-Chlorophenyl)-1-cyanothioformamide(4999-62-6)

Safety Data

• Hazardous Substances Data: 4999-62-6(Hazardous Substances Data)

Upstream product

• 13037-55-3 3-(4-chloro-phenyl)-2-thioxo-thiazolidin-4-one 
• 1075256-87-9 5-[2-(4-bromophenyl)-2-oxoethyl]-3-(4-chlorophenyl)-2-thioxo-1,3-thiazolidin-4-one 
• 174969-54-1 5-(4-chlorophenyl)imino-4-chloro-5H-1,2,3-dithiazole 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 

Downstream Products

• 872042-39-2 3-(4-chloro-phenyl)-1-phenyl-4-thioxo-imidazolidin-2-one 
• 1310368-80-9 1-(4-chlorophenyl)-4-imino-3-(4-(methylthio)phenyl)-5-thioxoimidazolidin-2-one 
• 1310368-82-1 1-(4-chlorophenyl)-4-imino-5-thioxo-3-p-tolylimidazolidin-2-one 
• 1310368-81-0 1-(4-chlorophenyl)-4-imino-3-(4-methoxyphenyl)-5-thioxoimidazolidin-2-one 
• 1310368-83-2 3-benzyl-1-(4-chlorophenyl)-4-imino-5-thioxoimidazolidin-2-one 
• 1328894-62-7 1-(4-chlorophenyl)-3-(4-fluorophenyl)-5-thioxoimidazolidine-2,4-dione 
• 1328894-53-6 1-(4-chlorophenyl)-3-(4-fluorophenyl)-4-imino-5-thioxoimidazolidin-2-one 
• 291283-04-0 [3-(4-chloro-phenyl)-5-imino-2,4-dithioxo-imidazolidin-1-yl]-phenyl-methanone 
• 116709-13-8 1-(3-chlorophenyl)-3-(4-chlorophenyl)-5-imino-2,4-imidazolidinedithione 

Relevant articles and documents

Studies on 4-thiazolidinones: Scope of the reactions of 3-aryl-2-thioxo-1,3-thiazolidin-4-ones with cyanide and cyanate ions

Treatment of 3-aryl-2-thioxo-1,3-thiazolidin-4-ones 1 with CN- and NCO- effected the ring cleavage providing [(cyanocarbonothioyl) amino]benzenes 4 and arylisothiocyanates 5, respectively. Similar treatment of 5-(2-aryl-2-oxoethyl) derivatives 2 afforded 2,4-bis(2-aryl-2-oxoethylidene) cyclobutane-1,3-diones 6 along with each of the preceding products. Treatment of the respective (E,Z)-5-(2-aryl-2-oxoethylidene) analogues 3b and 3c with CN- gave 4b and 4c and 2-(arylcarbonyl)-2-methoxy-4- oxopentanedinitriles 7b and 7c, in addition to 3,6-bis[2-(4-chlorophenyl)-1- methoxy-2-oxoethylidene]-1,4-dithiane-2,5-dione 8c, which has been generated from 3c. Reactions of 3c or 3d with NCO- provided 5c or 5d, together with 8c or 8d as pure isomers. In the formation of the MeO products 7 and 8, the solvent (MeOH) has participated. Structures of these products are based on microanalytical and spectroscopic data. Rationalizations for the above transformations are given.