107526-15-8Relevant academic research and scientific papers
Phosphoramidate dinucleosides as hepatitis C virus polymerase inhibitors
Zlatev, Ivan,Dutartre, Hélène,Barvik, Ivan,Neyts, Johan,Canard, Bruno,Vasseur, Jean-Jacques,Alvarez, Karine,Morvan, Fran?ois
supporting information; experimental part, p. 5745 - 5757 (2009/09/29)
GC dinucleosides exhibiting a phosphoramidate internucleosidic linkage with neutral, amphiphile, positively or negatively charged side chains were synthesized. Their potential inhibitory effect on the hepatitis C virus (HCV) NS5B polymerase was evaluated
Synthesis, characterization, and biological properties of small branched RNA fragments containing chiral (Rp and Sp) 2′,5′-phosphorothioate linkages
Mourani, Rawan,Damha, Masad J.
, p. 203 - 229 (2007/10/03)
Synthetic branched RNA fragments were prepared to examine the stereochemical requirements for hydrolysis of RNA lariats by the yeast debranching enzyme (yDBR). Specifically, two branched trinucleoside diphosphates and a tetranucleoside triphosphate contai
