107553-61-7

Basic information

• Product Name: 4-(N-Chloroacetylamino)methyl-2-thiophene carboxylic acid
• CAS NO: 107553-61-7
• Molecular Weight: 233.675
• Mol File: 107553-61-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(N-Chloroacetylamino)methyl-2-thiophene carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-Chloroacetylamino)methyl-2-thiophene carboxylic acid(107553-61-7)
• EPA Substance Registry System: 4-(N-Chloroacetylamino)methyl-2-thiophene carboxylic acid(107553-61-7)

Safety Data

• Hazardous Substances Data: 107553-61-7(Hazardous Substances Data)

Upstream product

• 527-72-0 2-thiophenylcarboxylic acid 
• 2832-19-1 2-Chloro-N-(hydroxymethyl)acetamide 

Relevant articles and documents

REACTIONS OF AROMARTIC AND HETEROAROMATIC COMPOUNDS CARRYING ELECTRON-ACCEPTOR SUBSTITUENTS. 26.ACYLAMINOMETHYLATION OF 2-ACYLTHIOPHENES,2-THIOPHENECARBOXYLIC ACID, AND ITS ESTERS.

The reaction of 2-thiophene aldehyde, 2-acetylthiophene, 2-thiophene carboxylic acid, and its methyl ester with N-(hydroxymethyl)chloroacetamide in concentrated sulfuric acid yields a mixture of 4- and 5-(N-chloroacetylamino)methyl derivatives, the former being preferred.