107553-63-9Relevant academic research and scientific papers
REACTIONS OF AROMARTIC AND HETEROAROMATIC COMPOUNDS CARRYING ELECTRON-ACCEPTOR SUBSTITUENTS. 26.ACYLAMINOMETHYLATION OF 2-ACYLTHIOPHENES,2-THIOPHENECARBOXYLIC ACID, AND ITS ESTERS.
Gol'dfarb, Ya. L.,Yakubov, A. P.,Belen'kii, L. I.
, p. 625 - 629 (1986)
The reaction of 2-thiophene aldehyde, 2-acetylthiophene, 2-thiophene carboxylic acid, and its methyl ester with N-(hydroxymethyl)chloroacetamide in concentrated sulfuric acid yields a mixture of 4- and 5-(N-chloroacetylamino)methyl derivatives, the former being preferred.
