107612-97-5

Upstream product

• 107612-96-4 C₂₁H₂₂O₄S 
• 107612-96-4 (1RS,2RS,5RS)-3'-acetoxy-4'-ethyl-4'-phenylthio-3',4'-dihydrobicyclo<3.3.0>octa-3,7-diene-2-spiro-2'-furan-5'-(2'H)-one 
• 62675-40-5 2-(phenylthio)butanoic acid 

Downstream Products

• 120584-72-7 (1RS,2RS,5RS,7SR,8RS)-4'-ethyl-3',7,8-trihydroxy-4'-phenylthio-3',4'-dihydrobicyclo<3.3.0>oct-3-ene-2-spiro-2'-furan-5'(2'H)-one 
• 86971-79-1 (+/-)-allamcin 

Relevant academic research and scientific papers

A Total Synthesis of Allamcin. An Approach to Antileukaemic Iridoid Lactones and Formal Syntheses of Plumericin and Allamandin

A total synthesis of the iridoid lactone (+/-)-allamcin (3) found in Allamanda neriifolia is described.Starting from the readily available bicyclooctenone (10), the synthesis uses a strategy based on: (i) elaboration of the key acetoxy-aldhyde inte