107627-72-5Relevant articles and documents
Disulfide-trapping identifies a new, effective chemical probe for activating the nuclear receptor human LRH-1 (NR5A2)
De Jesus Cortez, Felipe,Suzawa, Miyuki,Irvy, Sam,Bruning, John M.,Sablin, Elena,Jacobson, Matthew P.,Fletterick, Robert J.,Ingraham, Holly A.,England, Pamela M.
, (2016)
Conventional efforts relying on high-throughput physical and virtual screening of large compound libraries have failed to yield high-efficiency chemical probes for many of the 48 human nuclear receptors. Here, we investigated whether disulfide-trapping, a
