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107680-30-8

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107680-30-8 Usage

Description

(2S,3R)-1,3-bis(4-chlorophenyl)-2-(4-fluorophenyl)-4-(1H-1,2,4-triazol-1-yl)butane-2,3-diol, also known as posaconazole, is a triazole antifungal medication with a broad spectrum of activity against various fungal pathogens. It works by interfering with the synthesis of ergosterol, a crucial component of fungal cell membranes, leading to the disruption of the membrane structure and ultimately the death of the fungus.

Uses

Used in Antifungal Treatments:
Posaconazole is used as an antifungal agent for the treatment of a variety of fungal infections, including aspergillosis, candidiasis, and certain types of mold infections. It is particularly effective in immunocompromised patients who are more susceptible to these infections.
Used in Pharmaceutical Industry:
Posaconazole is used as a pharmaceutical agent in the development and formulation of antifungal medications. It is available in both oral and intravenous formulations, providing flexibility in treatment options for patients.
Used in Hospital Settings:
Posaconazole is commonly used in hospital settings to treat patients with severe or life-threatening fungal infections, particularly those who are immunocompromised and at a higher risk of developing such infections.
Used in Research and Development:
Posaconazole serves as a valuable compound in research and development for the discovery of new antifungal agents and the study of fungal pathogenesis and resistance mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 107680-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,6,8 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 107680-30:
(8*1)+(7*0)+(6*7)+(5*6)+(4*8)+(3*0)+(2*3)+(1*0)=118
118 % 10 = 8
So 107680-30-8 is a valid CAS Registry Number.

107680-30-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3R)-1,3-bis(4-chlorophenyl)-2-(4-fluorophenyl)-4-(1,2,4-triazol-1-yl)butane-2,3-diol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:107680-30-8 SDS

107680-30-8Downstream Products

107680-30-8Relevant articles and documents

Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds

Ogata,Matsumoto,Takahashi,Shimizu,Kida,Murabayashi,Shiro,Tawara

, p. 1054 - 1068 (2007/10/02)

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