107688-45-9Relevant academic research and scientific papers
Highly Efficient Construction of the 7-Azabicyclonon-2-ene System. An Application to the Synthesis of the AEF Ring System of Aconitine-type Diterpene Alkaloids
Shishido, Kozo,Hiroya, Kou,Fukumoto, Keiichiro,Kametani, Tetsuji
, p. 867 - 893 (2007/10/02)
The Mannich-type cyclisation of the cyclohexenylamine hydrochlorides (3 and 6) with 37percent aqueous formaldehyde in acetic acid at 150 deg C in a sealed tube afforded the bicyclic amines (9 and 10) in excellent yields.Under the same conditions, the amin
AN EFFICIENT AND HIGHLY REGIOSELECTIVE INTRAMOLECULAR MANNICH-TYPE REACTION: A CONSTRUCTION OF THE AEF RING SYSTEM OF ACONITINE-TYPE DITERPENE ALKALOIDS
Shishido, Kozo,Hiroya, Kou,Fukumoto, Keiichiro,Kametani, Tetsuji
, p. 1167 - 1170 (2007/10/02)
An efficient and highly regioselective intramolecular Mannich-type reaction has been developed.The utility of the methodology, combined with a stereoselective intramolecular Diels-Alder reaction, for the construction of the AEF ring system of aconitine-type alkaloids has been exemplified.
