107752-91-0

Upstream product

• 2826-22-4 4-fluorobenzylidenemalononitrile 
• 504-02-9 1,3-cylohexanedione 
• 459-57-4 4-fluorobenzaldehyde 
• 109-77-3 malononitrile 
• 30182-67-3 1,3-Cyclohexanedione 

Relevant academic research and scientific papers

MCM-41@Schiff base-Co(OAc)2 as an efficient catalyst for the synthesis of pyran derivatives

Heterogeneous ordered mesoporous silica materials catalyst, MCM-41@Schiff base-Co(AcO)2, reveals high catalytic performance within the synthesis of pyran derivatives using the multicomponent reaction of aldehydes, malononitrile and 2-naphthol (

A cytochrome c-urea functionalized dipeptide conjugate: An efficient HBD framework to synthesize 4: H -pyrans via one-pot multicomponent reaction

This work is focused on the development of an efficient and green protocol for the one-pot multicomponent synthesis of a series of 4H-pyran derivatives. Herein, a protein-peptide conjugate (SS1-Cyt. c) is synthesized and characterized using Circular Dichr

Synthesis, molecular modeling and BACE-1 inhibitory study of tetrahydrobenzo[b] pyran derivatives

β-Secretase (BACE1) has been broadly documented as one of the possible therapeutic targets for the treatment of Alzheimer's disease. In this paper, we report the synthesis and the for β-secretase (BACE-1) inhibitory activity of new series of tetrahydroben

Anion-cation co-operative catalysis by artificial sweetener saccharine-based ionic liquid for sustainable synthesis of 3,4-dihydropyrano[: C] chromenes, 4,5-dihydropyrano[4,3- b] pyran and tetrahydrobenzo [b] pyrans in aqueous medium

In this study, a saccharine-based ionic liquid [Bmim]Sac has been found to be a sustainable catalyst for the synthesis of 3,4-dihydropyrano[c]chromenes, 4,5-dihydropyrano[4,3-b]pyran and tetrahydrobenzo[b]pyrans scaffolds through Domino Knoevenagel-Michae

Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor

In view of developing effective xanthine oxidase (XO) enzyme inhibitors, a series of 100 pyrano[3,2-d]pyrimidine derivatives was synthesized and evaluated for its in vitro XO enzyme inhibition. Structure activity relationship has also been established. Am

Benzopyran compound and application thereof

The invention relates to a benzopyran compound and application thereof. The benzopyran compound has a structure formula shown in a formula I. The application is the application of the compound in preparing a biological membrane medicine for resisting the

Cheap thiamine hydrochloride as efficient catalyst for synthesis of 4H-benzo[b]pyrans in aqueous ethanol

Preparation of pharmaceutically active 2-amino-4H-pyran derivatives has been achieved using cheap thiamine hydrochloride as catalyst. A wide range of aromatic aldehydes easily undergo condensation with malononitrile and several kinds of 1,3-cyclohexanedio

Synthesis, Characterization, and Catalytic Behavior of Bamboo Rice Husk Ash

In this paper, we report the use of bamboo rice husk ash as an efficient, greener, reusable, and biodegradable heterogeneous catalyst for the synthesis of tetrahydro-4H-chromene-3-carbonitriles via the one-pot three-component reaction of malononitrile wit

4-Dialkylaminopyridine modified magnetic nanoparticles: As an efficient nano-organocatalyst for one-pot synthesis of 2-amino-4: H -chromene-3-carbonitrile derivatives in water

A novel heterogeneous magnetic nano-organocatalyst was developed using immobilization of 4-dialkylaminopyridine moieties on Fe3O4 magnetic nanoparticles (MNP-DMAP). It was synthesized using the reaction of MNP-oxiran (MNPO) with N-methylpyridin-4-amine. The MNPO substrate was produced via oxidation of vinyl groups on the surface of vinyl-functionalized MNP (VMNP) using H2O2. To synthesis VMNP, silica-coated magnetic nanoparticles (Fe3O4@SiO2) were reacted with trimethoxy(vinyl)silane. The MNP-DMAP catalyst shows remarkable activity in the synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives using a multicomponent reaction under mild conditions in water as a green solvent. The MNP-DMAP was reusable in this process for at least 10 times without any treatment in its catalytic activity.

Click and facile access of substituted tetrahydro-4H-chromenes using 2-aminopyridine as a catalyst

Abstract: A highly convenient and greener method for the facile synthesis of pharmaceutically diverse 2-amino-5-oxo-4-aryl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitriles via a one-pot, three component condensation of aromatic aldehydes, malononitrile, and