107752-98-7

Usage

Properties

1. Chemical compound with a complex molecular structure
2. Contains an amino group, a fluorophenyl group, and a carbonitrile group
3. Contains a chromene ring and a carbonyl functional group
4. Potential biological activity
5. Potential candidate for medicinal chemistry and drug development

Specific content

1. Amino group: NH2
2. Fluorophenyl group: -C6H4F
3. Carbonitrile group: -C≡N
4. Chromene ring structure: containing one oxygen atom and five carbon atoms in a cyclic arrangement
5. Carbonyl functional group: C=O
6. Dimethyl groups: two -CH3 groups attached to the chromene ring
7. Tetrahydro structure: four hydrogen atoms attached to the chromene ring
8. Potential interaction with biological targets such as enzymes or receptors

Upstream product

• 2972-71-6 3-fluorobenzylidenemalononitrile 
• 126-81-8 dimedone 
• 109-77-3 malononitrile 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant academic research and scientific papers

Efficient and green synthesis of 4H-pyran derivatives under ultrasound irradiation in the presence of K2CO3 supported on acidic montmorillonite

Acid-treated montmorillonite coating with K2CO3 is used as a catalyst for an efficient, rapid, one-pot synthesis of 4H-pyran derivatives in good yield under ultrasonic irradiation. The catalyst is environmentally benign, easy handlin

An eco-friendly innovative halide and metal-free basic ionic liquid catalyzed synthesis of tetrahydrobenzo [b] pyran derivatives in aqueous media: A sustainable protocol

A novel imidazolium-based highly efficient, recoverable, and reusable basic ionic liquid [PEMIM][OH] was synthesized using a very simple approach. This ionic liquid was employed as a catalyst for the multicomponent synthesis of tetrahydrobenzo[b]pyran der

Mechanical ball milling auxiliary synthesis method 2 -amino -3 - cyano - 4H - pyran compound

The invention relates to the technical field of chemical synthesis, and aims to solve the problems that 2 - amino -3 - cyano - 4H - pyran compounds are large in pollution and tedious in preparation in the prior art, and discloses a mechanical ball milling auxiliary synthesis method 2 -amino -3 - cyano - 4H - pyran compound which comprises the following steps: (a) the substrate 1. The substrate 2 and malononitrile were subjected to mechanical ball milling after addition of a protein catalyst and a grinding aid as a raw material. (b) Ball milling, the reactants are scraped off, the solvent is added, and the solvent is added, and after filtration, 2 - amino -3 - cyano - 4H - pyran compounds are prepared by column chromatography. The mechanical ball milling technology facilitates mutual contact of reactant molecules, realizes no solvent reaction, and is easily available to the environment. The method effectively realizes the green synthesis of 2 - amino -3 - cyano - 4H - pyran compounds, and is mild in preparation conditions, simple and convenient to operate and high in reaction rate.

Magnetic core-shell titanium dioxide nanoparticles as an efficient catalyst for domino Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and dimedone

Magnetic core-shell titanium dioxide nanoparticles (Fe3O4@SiO2@TiO2) were efficiently used for the preparation of tetrahydrobenzo[b]pyran derivatives via a one-pot three component condensation reaction of variou

Synthesis and luminescence of 4H-benzo[b]pyran derivatives catalyzed by Silica sulfuric acid in aqueous media

Silica sulfuric acid (SSA) was used as efficient catalyst for the synthesis of 4Hbenzo[b]pyran derivatives via the one-pot three-component condensation of aromatic aldehyde (1), 5,5-dimethyl-1,3-cyclohexanedione (2a) or 1,3-cyclohexandione (2b) and malono

Synthesis and luminescence of 4H-Benzo[b]pyran derivatives catalyzed by silica sulfuric acid in aqueous media

Silica sulfuric acid (SSA) was used as efficient catalyst for the synthesis of 4Hbenzo[ b]pyran derivatives via the one-pot three-component condensation of aromatic aldehyde (1), 5,5-dimethyl-1,3-cyclohexanedione (2a) or 1,3-cyclohexandione (2b) and malon

CYCLIZATION OF NITRILES. XX. SYNTHESIS OF CONDENSED 2-AMINO-4H-PYRANS AND THE MOLECULAR STRUCTURE OF 2-AMINO-7,7-DIMETHYL-4-(3-FLUOROPHENYL)-5-OXO-3-ETHOXYCARBONYL-5,6,7,8-TETRAHYDRO-4H-BENZOPYRAN

2-Amino-5,6,7,8-tetrahydro-4H-benzopyrans were obtained by the reaction of 1,3-cyclohexanedione and its substituted derivatives with the arylidene derivatives of malononitrile and ethyl cyanoacetate.The crystal structure of 2-amino-7,7-dimethyl-4-(3-fl