107771-03-9Relevant articles and documents
Silica gel accelerated aza-Michael addition of amines to α,β-unsaturated amides
You, Lisha,Feng, Song,An, Rui,Wang, Xinhong,Bai, Donglu
, p. 5147 - 5149 (2008)
A novel method to synthesize β-amino amide has been developed via conjugated addition of amine to bulky α,β-unsaturated amides promoted by silica gel. The silica gel worked efficiently to accelerate the reaction and afforded the related adduct in good to excellent yield.
