1078132-15-6

Basic information

• Product Name: C₁₈H₁₅ClN₂O₂
• CAS NO: 1078132-15-6
• Molecular Weight: 326.782
• Mol File: 1078132-15-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₅ClN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₅ClN₂O₂(1078132-15-6)
• EPA Substance Registry System: C₁₈H₁₅ClN₂O₂(1078132-15-6)

Safety Data

• Hazardous Substances Data: 1078132-15-6(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 86-92-0 3-methyl-1-(4-methylphenyl)-2-pyrazolin-5-one 

Relevant articles and documents

Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis

As a continuation of our previous work that turned toward the identification of antimycobacterial compounds with innovative structures, two series of pyrazole derivatives were synthesized by parallel solution-phase synthesis and were assayed as inhibitors of Mycobacterium tuberculosis (MTB), which is the causative agent of tuberculosis. One of these compounds showed high activity against MTB (MIC = 4 μg/mL). The newly synthesized pyrazoles were also computationally investigated to analyze their fit properties to the pharmacophoric model for antitubercular compounds previously built by us and to refine structure-activity relationship analysis.