1078138-89-2Relevant academic research and scientific papers
Asymmetric cycloadditions of o-quinone methides employing chiral ammonium fluoride precatalysts
Alden-Danforth, Ethan,Scerba, Michael T.,Lectka, Thomas
supporting information; experimental part, p. 4951 - 4953 (2009/05/31)
(Chemical Equation Presented) The catalytic, enantioselective, [4+2] cycloaddition reaction of ortho-quinone methides with silyl ketene acetals is described. This mechanistically interesting reaction, initiated by a chiral cinchona alkaloid-derived ammonium fluoride "precatalyst" complex, affords a variety of alkyl- and aryl-substituted 3,4-dihydrocoumarin products in excellent yield and with good enantioselectivity.
