107833-73-8

Basic information

• Product Name: 3-Nitropropanaldiethylacetal
• Synonyms: 3-Nitropropanaldiethylacetal
• CAS NO: 107833-73-8
• Molecular Formula: C₇H₁₅NO₄
• Molecular Weight: 177.1983
• Mol File: 107833-73-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Nitropropanaldiethylacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitropropanaldiethylacetal(107833-73-8)
• EPA Substance Registry System: 3-Nitropropanaldiethylacetal(107833-73-8)

Safety Data

• Hazardous Substances Data: 107833-73-8(Hazardous Substances Data)

Upstream product

• 58657-26-4 3-nitropropionaldehyde 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 41365-75-7 aminopropane diethyl acetal 

Relevant articles and documents

Synthetic studies on statins. Part 1: A short and cyanide-free synthesis of atorvastatin calcium via an enantioselective aldol strategy

A short and cyanide-free enantioselective synthesis of atorvastatin calcium has been achieved starting from a commercially available highly substituted 1,4-diketone in an overall yield of 40%. The key step in this approach is the asymmetric aldol reaction of an aldehyde with diketene in the presence of Ti(O-i-Pr)4-Schiff base complex to create the (5R)-stereochemistry of atorvastatin calcium.

3-Nitropropanal and 3-Nitropropanol: Preparation of the Parent Compounds and Derivatives

3-Nitropropanal has been prepared for the first time by 1,4-nitrite addition to acrolein.Several acetals of 3-nitropropanal are described, as well as 3-nitropropanol and some of its ethers. 3-Nitropropanol has been obtained by borane-dimethyl sulfide reduction of both 3-nitropropanal and 3-nitropropanoic acid.These reactions make available a variety of nitro compounds known as, or expected to become, highly useful and versatile building blocks for organic syntheses.