107835-23-4Relevant academic research and scientific papers
REACTION OF 1-METHYLURACIL WITH PHENYLBENZHYDRAZONOYL CHLORIDE
Chernyshova, N. B.,Shibaev, V. N.
, p. 532 - 538 (2007/10/02)
The ambident anion of 1-methyluracil gives with phenylbenzhydrazonoyl chloride, depending on the conditions, the N-acylation product (polar solvent, room temperature), or the O-acylation product (nonpolar solvent, heating), which rearranges to a cytosine derivative.Convenient methods have been developed for the preparation of 6-methyl-1,3-diphenyl-5,6-dihydro-5-oxopyrimidotriazolium chloride, a fluorescent derivative of 1-methyluracil, from the N-acylation product, and for the rapid base cleavage of the uracil ring under very mild conditions.
