107835-30-3Relevant academic research and scientific papers
ASYMMETRICAL ALKYLATION OF 1--AZETHIDINONE-2
Romanova, N. N.,Budylin, V. A.,Grishina, G. V.,Potapov, V. M.,Demchuk, M. L.,et al.
, p. 495 - 499 (1986)
The methylation of the lithium derivative of azethidinone-2 which has a chiral substituent at the nitrogen atom is asymmetrical and leads, with an optical yield of 35percent, to diastereomeric 3-methylated azethidinones-2.The reaction of these compounds with Na in liquid ammonia gives enantiomeric 3-methylazethidinones which confirms that an asymmetrical synthesis has taken place.
