107847-06-3Relevant academic research and scientific papers
The Synthesis of Indolizines: The Reaction of α-Halo Pyridinium Salts with β-Dicarbonyl Species
Nugent, Richard A.,Murphy, Megan
, p. 2206 - 2208 (2007/10/02)
The reaction of β-keto esters and β-diketones with readily accessible 2-halo pyridinium salts in the presence of DBU serves as a rapid and convenient method for the synthesis of substituted indolizines.The use of diethyl malonate as the dicarbonyl component of the reaction enables the preparation of previously undescribed 2-hydroxyindolizines.
