1078710-37-8

Basic information

• Product Name: C₁₅H₂₅N₃O₃
• Synonyms: C₁₅H₂₅N₃O₃
• CAS NO: 1078710-37-8
• Molecular Weight: 295.382
• Mol File: 1078710-37-8.mol

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₅N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₅N₃O₃(1078710-37-8)
• EPA Substance Registry System: C₁₅H₂₅N₃O₃(1078710-37-8)

Safety Data

• Hazardous Substances Data: 1078710-37-8(Hazardous Substances Data)

Upstream product

• 556-56-9 allyl iodid 
• 1078710-35-6 1-[2'-aci-nitrocyclohexylimino]-2-(S)-methoxymethylpyrrolidine 

Relevant articles and documents

Stereoselective alkylations of chiral nitro imine and nitro hydrazone dianions. Synthesis of enantiomerically enriched 3-substituted 1-nitrocyclohexenes

(Chemical Equation Presented) Dianions of chiral nitro imines (generated by a combination of LDA and s-BuLi) underwent diastereoselective alkylation with methyl, butyl, isopropyl, allyl, and methallyl iodides. In contrast to the behavior of simple metalloenamines, the most selective auxiliary contained no coordinating groups but did possess a large steric difference between the two substituents. The yield and selectivity of the alkylations were improved by the addition of HMPA or DMPU. The use of (S)-1-naphthylethylamine as the auxiliary afforded the R absolute configuration of the alkylation products. This stereochemical outcome could be rationalized by simple steric approach controlled alkylation in a conformationally fixed, internally coordinated dianion. A SAMP nitro hydrazone gave poorer yields and selectivities.