1078725-44-6

Basic information

• Product Name: C₂₂H₂₃F₄NO₄
• Synonyms: C₂₂H₂₃F₄NO₄
• CAS NO: 1078725-44-6
• Molecular Weight: 441.423
• Mol File: 1078725-44-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₃F₄NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₃F₄NO₄(1078725-44-6)
• EPA Substance Registry System: C₂₂H₂₃F₄NO₄(1078725-44-6)

Safety Data

• Hazardous Substances Data: 1078725-44-6(Hazardous Substances Data)

Upstream product

• 1078725-43-5 C₂₃H₂₅F₄NO₄ 
• 1078725-39-9 C₂₂H₂₄FNO₄ 
• 1078725-40-2 C₁₄H₁₉FO₃ 
• 1078725-41-3 C₁₅H₁₉FO₄ 
• 1078725-42-4 C₁₅H₁₉FO₅ 
• 331-64-6 2-fluoro-4-methoxy-benzaldehyde 

Downstream Products

• 1078725-45-7 C₂₃H₂₃F₄NO₄ 
• 1078725-47-9 C₂₄H₂₅F₄NO₄ 
• 1078725-49-1 C₂₁H₁₉F₄NO₄ 
• 1078725-50-4 C₂₂H₂₁F₄NO₄ 
• 1078725-46-8 C₂₄H₂₆BrF₄NO₄ 

Relevant articles and documents

Peroxisome proliferator-activated receptor (PPAR) agonists with 3,4-dihydro-2H-benzo[e][1,3]oxazine and 2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine skeletons: Effects of cyclization of linker moiety on ppar-agonistic activity

Conformationally restricted heterocyclic derivatives of KCL ((S)-2-{4-methoxy-3-[4-(trifluoromethyl)benzylcarbamoyl]benzyl}butanoic acid), which exhibit selective PPARα-agonistic activity, were prepared to examine the significance of the amide bond of KCL. In vitro transactivation assay clearly indicated that introduction of a 2-position fluorine atom enhanced PPARs-agonistic activity as expected, while cyclization of the amide bond caused a drastic decrease of PPARs-agonistic activity. The Japan Institute of Heterocyclic Chemistry.