1079039-19-2

Upstream product

• 20357-20-4 5-bromo-2-nitrobenzaldehyde 
• 3132-99-8 m-bromobenzoic aldehyde 

Downstream Products

• 1373844-49-5 5-cyclopropyl-2,4-dinitrobenzaldehyde 
• 1621705-67-6 5-bromo-3-cyano-2-(4-fluorophenyl)-6-nitro-2H-indazole 1-oxide 
• 1621704-45-7 5-(11-fluoro-5,6-dihydroindolo[1,2-h][1,7]naphthyridin-2-yl)-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)-2H-indazole-3-carboxamide 
• 1621705-72-3 2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole-3-carboxamide 
• 1621705-71-2 5-bromo-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)-2H-indazole-3-carboxamide 
• 1373839-59-8 5-bromo-2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)-2H-indazole-3-carboxamide 
• 1621705-70-1 6-amino-5-bromo-2-(4-fluorophenyl)-N-methyl-2H-indazole-3-carboxamide 
• 1621705-69-8 6-amino-5-bromo-2-(4-fluorophenyl)-2H-indazole-3-carboxylic acid 
• 1621705-68-7 6-amino-5-bromo-2-(4-fluorophenyl)-2H-indazole-3-carbonitrile 
• 1373845-44-3 5-bromo-2-(4-fluorophenyl)-6-nitro-2H-indazole-3-carbonitrile 
• 1373839-90-7 2-(4-chlorophenyl)-5-cyclopropyl-6-[3,3-difluoropropyl(methylsulfonyl)amino]-N-methylindazole-3-carboxamide 
• 1373839-92-9 2-(4-chlorophenyl)-5-cyclopropyl-6-[3-fluoropropyl(methylsulfonyl)amino]-N-methyl-2H-indazole-3-carboxamide 
• 1373846-06-0 2-(4-chlorophenyl)-5-cyclopropyl-N-methyl-6-[methylsulfonyl(3-oxopropyl)amino]indazole-3-carboxamide 
• 1373839-88-3 5-cyclopropyl-6-[(3-hydroxypropyl)(methylsulfonyl)amino]-2-(4-methoxyphenyl)-N-methyl-2H-indazole-3-carboxamide 

Relevant academic research and scientific papers

TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C

The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF HEPATITIS C

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

VIRAL POLYMERASE INHIBITORS

The present invention relates to viral polymerase inhibitors of formula (I) or salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections

VIRAL POLYMERASE INHIBITORS

The present invention relates to viral polymerase inhibitors of formula (I), salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections: (I)

Substituted 2-nitrobenzyltrichloroacetate esters for photodirected oligonucleotide detritylation in solid films

Oligonucleotide microarray fabrication by chemical synthesis using photoacid generators in solid films could have advantages over existing methods, but has not matched the accuracy of conventional synthesis where detritylation is performed with acid solut