20357-20-4

Basic information

• Product Name: 2-NITRO 5-BROMO-BENZALDEHYDE
• Synonyms: 2-NITRO 5-BROMO-BENZALDEHYDE;5-BROMO-2-NITRO-BENZALDEHYDE;CU48750000;Benzaldehyde, 5-broMo-2-nitro-
• CAS NO: 20357-20-4
• Molecular Formula: C₇H₄BrNO₃
• Molecular Weight: 230.02
• Mol File: 20357-20-4.mol
• Article Data: 34

Chemical Properties

• Melting Point: 71.0 to 75.0 °C
• Boiling Point: 330.5 °C at 760 mmHg
• Flash Point: 153.7 °C
• Appearance: /
• Density: 1.781 g/cm³
• Vapor Pressure: 0.000166mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 2-NITRO 5-BROMO-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO 5-BROMO-BENZALDEHYDE(20357-20-4)
• EPA Substance Registry System: 2-NITRO 5-BROMO-BENZALDEHYDE(20357-20-4)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• RTECS: CU4875000
• Hazardous Substances Data: 20357-20-4(Hazardous Substances Data)

Usage

Description

2-Nitro 5-Bromo-Benzaldehyde, with the molecular formula C7H4BrNO3, is a yellow solid chemical compound characterized by a benzene ring with a nitro and bromo group substitution, along with an aldehyde functional group. It is recognized for its potential as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. Additionally, it exhibits antibacterial and antifungal properties, making it a candidate for the development of new drugs for various diseases. However, due to its potential hazards, it requires careful handling and use.

Uses

Used in Pharmaceutical Industry:
2-Nitro 5-Bromo-Benzaldehyde is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs for the treatment of different diseases. Its presence in the synthesis process aids in the creation of complex molecular structures that can target specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Nitro 5-Bromo-Benzaldehyde serves as an intermediate in the production of agrochemicals, which are essential for enhancing crop protection and improving agricultural yields.
Used in Dye and Pigment Production:
2-Nitro 5-Bromo-Benzaldehyde is utilized in the manufacturing process of dyes and pigments, providing a range of color options for various applications, including textiles, plastics, and printing inks.
Used in Antibacterial and Antifungal Applications:
Due to its inherent antibacterial and antifungal properties, 2-Nitro 5-Bromo-Benzaldehyde is used in the research and development of new drugs aimed at treating bacterial and fungal infections. Its potential in this area is currently being explored for more effective therapeutic solutions.

InChI:InChI=1/C7H4BrNO3/c8-6-1-2-7(9(11)12)5(3-6)4-10/h1-4H

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 3132-99-8 m-bromobenzoic aldehyde 
• 105205-48-9 [(E)-2-(5-bromo-2-nitro-phenyl)-vinyl]-dimethyl-amine 
• 51686-78-3 2,4-dibromonitrobenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 84-40-2 5,5'-dibromo-1H,1'H-[2,2']biindolylidene-3,3'-dione 
• 796873-09-1 2-methyl-5-bromo-2H-indazole-N-oxide 
• 910898-57-6 N-[(5-bromo-2-nitrophenyl)methylene]-4-fluoroaniline 
• 1184259-08-2 2-nitro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde 
• 1079039-18-1 5-bromo-2,6-dinitrobenzaldehyde 
• 1079039-19-2 5-bromo-2,4-dinitrobenzaldehyde 
• 113259-79-3 5-(piperidin-1-yl)-2-nitrobenzaldehyde 
• 113259-81-7 5-(N-morpholinyl)-2-nitrobenzaldehyde 
• 1020575-25-0 ethyl 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-3-methyl-2-quinolinecarboxylate 
• 1020575-19-2 ethyl 6-(4-hydroxyphenyl)-3-methyl-2-quinolinecarboxylate 
• 1020575-07-8 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-3-methyl-2-quinolinecarboxylic acid 
• 112768-14-6 4-Bromo-2-[(E)-2-(4-methoxy-phenyl)-vinyl]-1-nitro-benzene 
• 112768-11-3 6-bromo-3-(4-methoxyphenyl)-2H-chromen-2-one 
• 112768-01-1 4-bromo-1-nitro-2-vinylbenzene 

Relevant articles and documents

Friedlaender approach for the incorporation of 6-bromoquinoline into novel chelating ligands

Nitration of 3-bromobenzaldehyde followed by sodium dithionite reduction provides 5-bromo-2-aminobenzaldehyde, which undergoes the Friedlaender condensation with a variety of enolizable ketones to afford bidentate and tridentate 6-bromoquinoline derivativ

o-Nitrobenzyl photoremovable groups with fluorescence uncaging reporting properties

o-Nitrobenzyl (o-NB) derivatives are the most widely applied photoremovable groups for the study of dynamic biological processes. By introducing different substituents to the benzylic position we were able to generate a fluorescence signal upon irradiatio

Triazole derivative having HSP90 (Heat Shock Protein) inhibiting activity, as well as preparation method and application of triazole derivative

The invention discloses a triazole derivative having an HSP90 (Heat Shock Protein) inhibiting activity, as well as a preparation method and an application of the triazole derivative. Specifically, the invention relates to the triazole derivative having a structure as shown in a formula (I), a stereisomer of the triazole derivative and a pharmaceutically acceptable salt, wherein the definition of each substituent group in the formula (I) and the definition in a description are the same. The compound with a novel structure has the HSP90 inhibiting activity, can be used to cure cancers, neurodegenerative disorders, inflammation diseases, autoimmune diseases, ischemic brain injuries and the like, and has a broad application prospect.