107913-73-5

Upstream product

• 96700-91-3 3,5-dimethoxyphenol tert-butyldimethylsilyl ether 
• 870-63-3 prenyl bromide 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 500-99-2 3,5-dimethoxyphenol 

Downstream Products

• 138038-87-6 1-t-butyldimethylsilyloxy-3-hydroxy-5-methoxy-4-(3-methylbut-2-enyl)benzene 
• 94935-92-9 3,5-dimethoxy-4-(3-methyl-2-butenyl)phenol 
• 138038-90-1 2-<3-t-butyldimethylsilyloxy-5-methoxy-2-(3-methylbut-2-enyl)phenyl>-6-t-butyldiphenylsilyloxybenzofuran 
• 138038-88-7 1-t-butyldimethylsilyloxy-3-methoxy-4-(3-methylbut-2-enyl)-5-trifluoromethanesulphonyloxybenzene 
• 138038-89-8 2-<3-t-butyldimethylsilyloxy-5-methoxy-2-(3-methylbut-2-enyl)phenyl>benzofuran 
• 73338-88-2 moracin I 
• 107913-77-9 <<4-<1-<<3,5-dimethoxy-4-(3-methyl-2-butenyl)phenoxy>methyl>ethenyl>-1,3-phenylene>bis<<(oxymethylene)oxy>-2,1-ethanediyl>>bis(trimethylsilane) 

Relevant academic research and scientific papers

Transition metal mediated synthesis of some prenylated phytoalexins of Morus alba Linn.

Directed functionalisation of resorcinol and benzofuran rings was achieved by activation with a coordinated tricarbonylchromium(O) unit and vicinal or remote lithiation directed by methoxy or t-butyldiphenylsilyloxy groups respectively. The process was applied either before [to the geranylbenzofuran (16) for mulberrofuran B (5)] or after [for moracin C (2)] palladium catalysed coupling of the 2-stannylated benzofuran and the 5-iodinated resorcinol moieties. In addition moracin I (14) was synthesised by a Stille coupling of the stannylated benzofuran (6) with the phloroglucinol triflate (14). Application to the synthesis of albafuran A (3) gave, unexpectedly, the 3-geranylbenzofuran (11).

Total Synthesis of (+/-)-5-O-Methyllicoricidin

A novel intramolecular Mitsunobu alkylation is employed to construct the benzopyran moiety of the newly isolated isoflavan 5-O-methyllicoricidin.This convergent 15-step total synthesis outlines a chemically mild approach to the acid-sensitive isoflavanoid