107951-89-3

Upstream product

• 18598-23-7 ethyl (4-methoxyphenoxy)acetate 
• 150-76-5 4-methoxy-phenol 
• 21953-91-3 (4-methoxyphenoxy)acetic acid hydrazide 
• 3460-49-9 1-ethoxy-4-isothiocyanatobenzene 

Downstream Products

• 107952-01-2 4-(4-Ethoxy-phenyl)-5-(4-methoxy-phenoxymethyl)-4H-[1,2,4]triazole-3-thiol 

Relevant academic research and scientific papers

Synthesis of Some New Substituted Mercaptotriazoles and Thiazolidones and Their Monoamine Oxidase Inhibitory and Anticonvulsant Properties

A number of 4-aryl-5-aryloxymethyl-3-mercapto-1,2,4(H)-triazoles (IV) and 2-arylimino-3-aryloxyacetamido-4-thiazolidones (V) have been synthesized.Some of these compounds inhibit rat brain monoamine oxidase (MAO) in vitro at a final concentration of 1E-3 mol/litre, but are found to be inactive against pentylenetetrazole induced seizures in mice at a dose of 80 mg/kg.

Synthesis of some New Substituted Thiosemicarbazides and Triazoles as Possible Anticonvulsants

Forteen 1-o/p-anisoxyacetyl-4-arylthiosemicarbazides and their corresponding 5-(o/p-anisoxymethyl)-4-aryl-3-mercapto-1,2,4(H)-triazoles were synthesized.Eight of these compounds, when screened against maximal electroshock and pentylenetetrazole-induced seizures in mice at a dose of 80 mg/kg were, however, found to be inactive.