107957-80-2Relevant academic research and scientific papers
Enantiodivergent syntheses of cycloheptenone intermediates for guaiane sesquiterpenes
Leiva de Faria, Mary,De A. Magalhaes, Ruy,Silva, Fernando C,De O. Matias, Luiz G,Ceschi, Marco A,Brocksom, Ursula,John Brocksom, Timothy
, p. 4093 - 4103 (2000)
The syntheses of enantiomeric 6-isopropenyl-3-methyl-2-cycloheptenones 16 and 22 have been effected starting from (R)-(-)-carvone. In the synthesis of 16, (R)-(-)-carvone was reduced and the resulting dihydrocarvone transformed regioselectively into silyl
Tri- and tetrasubstituted α-fluorocyclohexanones with enantiomeric excesses in the range of 97-100%
Solladie-Cavallo, Arlette,Jierry, Loc,Bouerat, Laetitia,Taillasson, Philippe
, p. 883 - 891 (2007/10/03)
The α-fluorinated trisubstituted ketones (2S,5R)-(-)-7-Ia, (2R,5R)-(+)-7-IIe, (2S,5R)-(-)-8-Ia and (2R,5R)-(+)-8-IIe were synthesised from (+)-dihydrocarvone (99% (R)-configuration at C-5) and fully characterised. α-Fluorinated tetrasubstituted ketones (-)-9-Ia, (+)-9-Ia, (+)-9-IIa and (+)-10-Ia having e.e.s of ≥97% were synthesised as racemates from 3-methyl cyclo-hexenone then resolved into the pure enantiomers using chiral HPLC and fully characterised.
1,5-DICARBONYL COMPOUNDS A GENERAL PREPARATION METHOD
Duhamel, P.,Hennequin, L.,Poirier, J. M.,Tavel, G.,Vottero, C.
, p. 4777 - 4786 (2007/10/02)
In this report, a general method for the preparation of 1,5-dicarbonyl compounds and six membered ring annelation is described.This method involves the reaction of hemiacetal vinylogs 1 with enol ethers 2 or 3 in the presence of a Lewis acid.This reaction was successfully applied to the enol ethers of α and α,α'-hindered ketones such as 2,2,6-trimethyl cyclohexanone. α-Cyperone and 6-epi-α-cyperone were obtained using this process.
