1080-08-6Relevant academic research and scientific papers
A structure-taste study of arylsulfonyl(cyclo)alkanecarboxylic acids
Lysiak, Violetta,Ratajczak, Aleksander,Mencel, Agnieszka,Jarzembek, Krystyna,Polanski, Jaroslaw
, p. 671 - 675 (2007/10/03)
A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1-phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.
Direct aromatic tert-butylation during the synthesis of thiochroman-4-ones
Clayton, Stephen E.,Gabbutt, Christopher D.,Hepworth, John D.,Mark Heron
, p. 939 - 946 (2007/10/02)
The synthesis of thiochroman-4-ones from thiophenols and 3-methylbut-2-enoic acid effected by methane sulphonic acid is accompanied by tert-butylation of the aromatic ring. 3-Arylthiobutanoic acids, available using β-butyrolactone, are efficiently cyclised in the same manner.
