108012-20-0Relevant academic research and scientific papers
Palladium-catalyzed phosphine-free direct C-H arylation of benzothiophenes and benzofurans involving MIDA boronates
Wang, Zhiwei,Li, Yabo,Yan, Beiqi,Huang, Mengmeng,Wu, Yangjie
, p. 531 - 536 (2015)
With high regioselectivity, a series of benzoheterocyclic compounds were synthesized via palladiium-catalyzed phosphine-free C-H arylation of benzothiophenes/benzofurans with aryl MIDA boronates at 30-50 °C in moderate to excellent yields. MIDA boronates were used in C-H arylation of heterocycles for the first time. Under the optimal conditions, the benzothiophenes could be transformed into the β-arylbenzothiophenes, and the benzofurans gave only α-aryl-substituted products.
An aryl thiol-vinyl azide coupling reaction and a thiol-vinyl azide coupling/cyclization cascade: efficient synthesis of β-ketosulfides and arene-fused 5-methylene-2-pyrrolidinone derivatives
Wang, Yong,Wang, Yu-Jiao,Liang, Xian-Chen,Shen, Mei-Hua,Xu, Hua-Dong,Xu, Defeng
, p. 5169 - 5176 (2021/06/21)
The addition reaction of thiol to vinyl azide has been extensively studied. Variously substituted aryl thiols are all viable for this coupling process. The scope of the other partner is successfully expanded from α-aryl vinyl azide to α-alkyl vinyl azide.
Novel syntheses of 2,3-disubstituted benzothiophenes
Katritzky,Kirichenko,Ji, Yu,Prakash
, p. 156 - 164 (2007/10/03)
The sodium salts of o-sulfanylphenyl ketones 3a-g were treated with α-benzotriazol-1-ylalkyl chlorides 4a,b to give intermediates 5a-k in good yields. Compounds 5a-k, on treatment successively with LDA and Ti (0), gave benzothiophenes 7a-k.
3-Phenyl benzo b thiophenes as pesticidal compounds
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, (2008/06/13)
Compounds of the general formula in which, X and Y each represents halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylenedioxy, alkylthio, halo- substituted alkylthio, alkylsulphinyl, halo-substituted alkylsulphinyl, alkylsulphonyl, halo-substituted alky
