33046-45-6

Upstream product

• 17530-89-1 p-tolyl phenacyl sulphoxide 
• 38325-59-6 4-methylphenylthiotrimethylsilane 
• 70-11-1 α-bromoacetophenone 
• 536-74-3 phenylacetylene 
• 16717-64-9 1-azidostyrene 
• 106-45-6 para-thiocresol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 98-86-2 acetophenone 
• 1021-45-0 phosphoric acid diethyl ester-(1-phenyl-vinyl ester) 
• 103-19-5 di(p-tolyl) disulfide 
• 120-46-7 1,3-diphenylpropanedione 
• 93-91-4 1-phenylbutan-1,3-dione 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 41103-87-1 1-phenyl-2-(p-tolylsulfinyl)ethan-1-ol 

Downstream Products

• 93-89-0 benzoic acid ethyl ester 
• 1586031-05-1 C₁₇H₁₈O₂S 
• 1046758-77-3 2,2-difluoro-1-phenyl-2-(p-tosyl)ethanone 
• 1248588-12-6 3-ethoxy-2-[(4-methylphenyl)sulfanyl]-1-phenylprop-2-en-1-one 
• 103-19-5 di(p-tolyl) disulfide 
• 108011-95-6 5-methyl-3-phenyl-benzo[b]thiophene-1,1-dioxide 
• 92697-23-9 5-methyl-2-phenylbenzo[b]thiophene-1,1-dioxide 
• 141362-05-2 (2,2-diphenyl-vinyl)-p-tolyl sulfoxide 
• 70312-74-2 1-(2,2-diphenyl-ethenesulfonyl)-4-methyl-benzene 
• 122772-72-9 (E)-3-(2-Chloro-phenyl)-1-phenyl-2-(toluene-4-sulfonyl)-propenone 
• 33155-82-7 1,3-diphenyl-2-tosyl-prop-2-en-1-one 
• 52154-24-2 (R)-p-tolylsulfinylacetophenone 
• 96938-09-9 (S)-(-)-2-(p-tolylsulfanyl)-1-phenylethanol 
• 51351-89-4 nitromethyl p-tolyl sulfone 

Relevant academic research and scientific papers

Electrocatalytic Synthesis of gem -Bisarylthio Enamines and α-Phenylthio Ketones via a Radical Process under Mild Conditions

The novel method for the synthesis of gem -bisarylthio enamines and α-phenylthio ketones was developed via the coupling of α-substituted vinyl azides with thiols in the presence of tetrabutylammonium iodide (TBAI) as a redox catalyst and electrolyte at ro

An aryl thiol-vinyl azide coupling reaction and a thiol-vinyl azide coupling/cyclization cascade: efficient synthesis of β-ketosulfides and arene-fused 5-methylene-2-pyrrolidinone derivatives

The addition reaction of thiol to vinyl azide has been extensively studied. Variously substituted aryl thiols are all viable for this coupling process. The scope of the other partner is successfully expanded from α-aryl vinyl azide to α-alkyl vinyl azide.

Practical and regioselective halo-trifluoromethylthiolation of sulfur ylides

A H2O mediated practical and highly regioselective chloro- and bromo-trifluoromethylthiolation of sulfur ylides is reported using a difunctionalization strategy. In the reaction sequence, sulfur ylides presumably react with an electrophilic trifluoromethylthiolating reagent to generate an α-SCF3 substituted sulfonium salt intermediate, which then undergoes a substitution with nucleophilic halogens. This journal is

Metal-Free Oxidative Thioesterification of Methyl Ketones with Thiols/Disulfides for the Synthesis of α-Ketothioesters

A direct Csp3-H bond oxidative thioesterification of methyl ketones with aromatic thiols/disulfides promoted by TBAI/K2S2O8 has been developed. The reaction provides successfully a simple and efficient method for the synthesis of functionalized α-ketothioesters of aromatic thiols. This practical methodology exhibits readily available starting materials, large-scale applicability, synthetic application, and broad functional group tolerance. A possible mechanism for the transformation is proposed.

Odorless, Regioselective Synthesis of Diaryl Sulfides and α-Thioaryl Carbonyls from Sodium Arylsulfinates via a Metal- Free Radical Strategy in Water

Regioselective arylthiolations of aromatic amines, arenols and ketones via C–H bond functionalization have been achieved with I2and PPh3in an aqueous system, whereby arylsulfenyl radicals are in situ generated from odorless sodium arylsulfinates. The arylsulfenyl radicals can react with free anilines containing electron-withdrawing groups and complex substrates (estrone and progesterone). Further experiments and quantum chemical calculations were also performed to deduce a mechanism for the formation of arylsulfenyl radicals. (Figure presented.).

Catalyst-Free Difunctionalization of Activated Alkenes in Water: Efficient Synthesis of β-Keto Sulfides and Sulfones

Difunctionalization of activated alkenes, a powerful strategy in chemical synthesis, has been accomplished for direct synthesis of a series of β-keto sulfides and β-keto sulfones. The transformation, mediated by O2, proceeds smoothly in water and without any catalyst. Prominent advantages of this method include mild reaction conditions, purification simplicity, and gram-scale synthesis, underlining the practical utility of this methodology.

Copper-Catalyzed Synthesis of α-Thioaryl Carbonyl Compounds Through S-S and C-C Bond Cleavage

A method to access α-thioaryl ketones and α-thioaryl esters employing copper acetate (hydrate) as catalyst and readily accessible diaryl disulfides and β-diketones (or β-keto esters) has been developed. Both alkyl- and aryl-substituted carbonyl compounds can be prepared. Copyright

Regioselective synthesis of 5-(arylsulfanyl)- and 5-(benzylsulfanyl)-6- phenylsalicylates by one-pot cyclizations of 1,3-bis(silyloxy)buta-1,3-dienes with 2-(arylsulfanyl)- and 5-(benzylsulfanyl)-3-ethoxy-1-phenylprop-2-en-1-ones

5-(Arylsulfanyl)-6-phenylsalicylates were prepared by one-pot cyclizations of 1,3-bis(trimethylsilyloxy) buta-1,3-dienes with 2-(arylsulfanyl)-3-ethoxy-1- phenylprop-2-en-1-ones.

An efficient fluorination of β-ketosulfones promoted by a room-temperature ionic liquid at ambient conditions under ultrasound irradiation using Selectfluor F-TEDA-BF4

The fluorination reaction involving a β-ketosulfones by Selectfluor was efficiently promoted by the ionic liquid, [Hbim]BF4 (IL) as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-β-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.