108107-63-7Relevant academic research and scientific papers
Phenyl Isothiocyanate - Mediated Cyclocondensation of Hippuric Acid in the Presence of Salicylaldehyde / o-Hydroxyacetophenone
Ashare, Ram,Mukerjee, Arya K.
, p. 423 - 424 (2007/10/02)
Hippuric acid (1), when heated with phenyl isothiocyanate (2) and salicylaldehyde (3a) at 170 deg for 30 min, affords 3-N-benzoylaminocoumarin (4a) and (Z)-4-(o-hydroxybenzylidene)-1,2-diphenyl-2-imidazolin-5-one (5). o-Hydroxyacetophenone affords hippuranilide as the main product, though 4b is discernible by TLC.
