35175-74-7

Upstream product

• 495-69-2 Hippuric Acid 
• 5663-67-2 2-acetoxybenzaldehyde 
• 1199-01-5 2-phenylazlactone 
• 90-02-8 salicylaldehyde 
• 108-24-7 acetic anhydride 
• 137401-65-1 (Z)-4-(2'-hydroxyphenylmethylene)-2-phenyloxazol-5(4H)-one 
• 119872-12-7 (Z)-2-benzoylamino-3-(2'-hydroxyphenyl)acrylic acid 

Downstream Products

• 137401-65-1 (Z)-4-(2'-hydroxyphenylmethylene)-2-phenyloxazol-5(4H)-one 
• 137551-89-4 ethyl (Z)-2-benzoylamino-o-hydroxycinnamate 
• 137551-88-3 ethyl (Z)-2-benzoylamino-o-acetoxycinnamate 
• 137551-87-2 S-benzyl (Z)-2-benzoylamino-o-(acetoxy)thiocinnamate 
• 2549-08-8 3-benzamidocoumarin 
• 70984-51-9 2-benzoylamino-o-hydroxycinnamic acid 
• 119872-12-7 (Z)-2-benzoylamino-3-(2'-hydroxyphenyl)acrylic acid 
• 137401-67-3 (Z)-2-benzoylamino-3-(2-hydroxyphenyl)acrylic acid methyl ester 
• 126325-42-6 4-(o-Hydroxybenzilidene)-1,2-diphenyl-2-imidazolin-5-one 
• 103-84-4 Acetanilid 
• 108107-63-7 N-Phenyl-2-benzoylamino-o-acetoxycinnamide 

Relevant academic research and scientific papers

Study on dry-media microwave azalactone synthesis on different supported KF catalysts: Influence of textural and acid-base properties of supports

Twenty-five inorganic solids studied as supports for KF were screened with respect to the synthesis of the azalactone obtained by dry-media condensation of p-hydroxybenzaldehyde with hippuric acid in acetic anhydride (1:1:4, molar ratio), in 3 g of 10 wt%

Alcohol uncaging with fluorescence reporting: Evaluation of o-acetoxyphenyl methyloxazolone precursors

(Chemical Equation Presented) This paper evaluates a series of photolabile protecting groups with built-in fluorescence reporting. They rely on readily available o-acetoxyphenyl methyloxazolones as activated precursors. Alcohol substrates are easily caged. The resulting photoactivable esters exhibit large one- and two-photon uncaging cross sections. The alcohol substrates are quantitatively released in a 1:1 molar ratio with a strongly fluorescent coumarin coproduct that serves as a reporter to quantify substrate delivery.

Reaction of unsaturated azlactones with sulfur nucleophiles: some observations

Unsaturated azlactones undergo thiolysis with toluene-α-thiol, but 2-substituted (Z)-4-o-acetoxybenzylidene-4,5-dihydrooxazol-5-ones form 3-acylaminocoumarins in the presence of triethylamine.Sodium sulfide in ethanol brings about ethanolysis of the 1,5 b

4-(2'-Hydroxyphenylmethylene)-2-phenyloxyzol-5(4H)-one: A Comedy of Errors

Eighteen publications since 1955 have described properties and reactions of the title compound.All these reports are erroneous and refer, variously, to three other substances.All literature reports of the analogous 4-(2'-hydroxyphenylmethylene)-2-methyloxazol-5(4H)-one also need revision.A convenient synthesis of the title compound 3 (R=H), its chemical and physical properties, and its rearrangement to 3-benzoylamino-1-benzopyran-2-one 1, are reported here for the first time.A mechanism is presented for the observed course of Ploechl-Erlenmeyer syntheses with salicylaldehyde and with 2-acetoxybenzaldehyde.

Thiol-induced Conversion of (Z)-4-o-Acetoxybenzylidene-2-phenyl-4,5-dihydrooxazol-5-ones into 3-Benzoylaminocoumarins

Toluene-α-thiol induces cleavage of the 1,5-bond of (Z)-4-o-acetoxybenzylidene-2-phenyl-4,5-dihydrooxazol-5-ones in triethylamine-containing ethanol to give 3-benzoylaminocoumarins.