108124-06-7Relevant academic research and scientific papers
Palladium-catalyzed double alkylation of 3-aryl-2-fluoroallyl esters with malonate nucleophiles through the carbon-fluorine bond cleavage
Yamamoto, Mitsuaki,Hayashi, Shunsuke,Isa, Kazuki,Kawatsura, Motoi
, p. 700 - 703 (2014)
The alkylation of (Z)-3-aryl-2-fluoroallyl acetate with the malonate anion by the [Pd(C3H5)(cod)]BF4/2,2′-bpy catalyst proceeds through the carbon-fluorine bond cleavage, and 2 equiv of the malonate nucleophile was introdu
Silver-mediated oxidative C-H/C-H functionalization: A strategy to construct polysubstituted furans
He, Chuan,Guo, Sheng,Ke, Jie,Hao, Jing,Xu, Huan,Chen, Hongyi,Lei, Aiwen
supporting information; experimental part, p. 5766 - 5769 (2012/05/07)
A novel silver-mediated highly selective oxidative C-H/C-H functionalization of 1,3-dicarbonyl compounds with terminal alkynes for the creation of polysubstituted furans and pyrroles in one step has been demonstrated. Promoted by the crucial silver specie
One-pot synthesis of furans using base- and acid-supported reagents Na 2CO3/Al2O3-PPA/SiO2'
Aoyama, Tadashi,Nagaoka, Takashi,Takido, Toshio,Kodomari, Mitsuo
experimental part, p. 619 - 625 (2011/04/15)
A convenient method for the one-pot synthesis of furans from -keto esters and -halo ketones was developed using an acid- and base-supported reagent system Na2CO3/Al2O3-PPA/SiO2'. The condensation reaction of triketones, which are formed from the reaction of -keto esters with -halo ketones in the presence of Na2CO 3/Al2O3, was promoted by PPA/SiO2 to give the corresponding furans in good yields. This method is simple and easy to perform in comparison with stepwise processes, and the yields are good.
Ionic liquid as catalyst and reaction medium: A Simple and Efficient Procedure for Paal-Knorr furan synthesis
Wang, Gangqiang,Guan, Zhi,Tang, Rongchang,He, Yanhong
experimental part, p. 370 - 377 (2010/04/04)
The ionic liquid 1-butyl-3-methyl-imidazolium hydrogen sulfate, [bmim]HSO4, efficiently catalyzes Paal-Knorr furan synthesis without any organic solvent. A wide range of aliphatic and aromatic 1,4-diketones easily undergo condensations to form furan derivatives, providing a general and convenient procedure. The Paal-Knorr reaction of ester-substituted 1,4-diketones is first reported. The ionic liquid can be recovered and reused for subsequent runs without any appreciable loss of efficiency.
