108147-32-6Relevant articles and documents
Potent Prostacyclin Analogues Based on the Bicyclooctane Ring System
Kluge, Arthur F.,Kertesz, Denis J.,O-Yang, Counde,Wu, Helen Y.
, p. 2860 - 2868 (2007/10/02)
The novel and biologically active prostacyclin mimetics 2 and 29 were prepared in a sequence based on the regioselective opening of epoxide 7 with a lithium acetylide in the presence of boron trifluoride etherate.The regioselectivity of epoxide opening wa