108175-82-2Relevant academic research and scientific papers
Kinase inhibitor, and preparation and application of kinase inhibitor
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Paragraph 0329-0331; 0344; 0345, (2018/09/11)
The invention provides a compound shown as a formula (I), or a stereoisomer, a tautomer, nitrogen oxide, metabolite, a prodrug, pharmaceutically acceptable salt or solvate of the compound, and application of the compound to preparing drugs or drug compositions for treating Pim kinase-mediated diseases.
Synthesis of 2-Aryl-6-carbethoxythiazolopyridine
Shafiee, A.,Ghazar, H.
, p. 1171 - 1173 (2007/10/02)
Startinf from readily available 2-aryl-5-formyl-4-methylthiazole, 2-aryl-6-carbethoxythiazolopyridine was prepared. β-(2-Phenylthiazol-4-yl)acrylic acid was converted to the corresponding azide (VI).Cyclization of compound VI afforded 2-phenylthiaz
