108175-97-9Relevant academic research and scientific papers
SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins
Yan, Su,Elmes, Matthew W.,Tong, Simon,Hu, Kongzhen,Awwa, Monaf,Teng, Gary Y.H.,Jing, Yunrong,Freitag, Matthew,Gan, Qianwen,Clement, Timothy,Wei, Longfei,Sweeney, Joseph M.,Joseph, Olivia M.,Che, Joyce,Carbonetti, Gregory S.,Wang, Liqun,Bogdan, Diane M.,Falcone, Jerome,Smietalo, Norbert,Zhou, Yuchen,Ralph, Brian,Hsu, Hao-Chi,Li, Huilin,Rizzo, Robert C.,Deutsch, Dale G.,Kaczocha, Martin,Ojima, Iwao
, p. 233 - 252 (2018/05/28)
Fatty acid binding proteins (FABPs) serve as critical modulators of endocannabinoid signaling by facilitating the intracellular transport of anandamide and whose inhibition potentiates anandamide signaling. Our previous work has identified a novel small-m
α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF
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Page/Page column 55, (2017/09/27)
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure : Formula (I)
PREPARATION OF CHLORO-α-TRUXILLIC ACIDS VIA 3-METHYL-4-NITRO-5-STYRYLISOXAZOLE PHOTODIMERS
Baracchi, Antonella,Chimichi, Stefano,Sio, Francesco De,Donati, Donato,Nesi, Rodolfo,et al.
, p. 2863 - 2870 (2007/10/02)
Chloro-α-truxillic acids (3b-e) were prepared by oxidation of the photodimers (2b-e) of 3-methyl-4-nitro-5-chlorostyrylisoxazoles (1b-e).
