108182-84-9

Basic information

• Product Name: Acetic acid (2R,3R,4R,5R)-3-chloro-5-(6-dibenzoylamino-purin-9-yl)-4-p-tolylsulfanyl-tetrahydro-furan-2-ylmethyl ester
• CAS NO: 108182-84-9
• Molecular Weight: 642.135
• Mol File: 108182-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3R,4R,5R)-3-chloro-5-(6-dibenzoylamino-purin-9-yl)-4-p-tolylsulfanyl-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3R,4R,5R)-3-chloro-5-(6-dibenzoylamino-purin-9-yl)-4-p-tolylsulfanyl-tetrahydro-furan-2-ylmethyl ester(108182-84-9)
• EPA Substance Registry System: Acetic acid (2R,3R,4R,5R)-3-chloro-5-(6-dibenzoylamino-purin-9-yl)-4-p-tolylsulfanyl-tetrahydro-furan-2-ylmethyl ester(108182-84-9)

Safety Data

• Hazardous Substances Data: 108182-84-9(Hazardous Substances Data)

Upstream product

• 933-00-6 p-methylbenzenesulfenyl chloride 
• 108182-79-2 6-N-dibenzoyl-9-(5'-O-acetyl-2',3'-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine 
• 98-88-4 benzoyl chloride 
• 108194-68-9 6-N-dibenzoyl-9-(2',5'-di-O-acetyl-3'-deoxy-3'-bromo-β-D-xylofuranosyl)adenine 
• 106-45-6 para-thiocresol 
• 62805-48-5 9-(2,5-di-O-acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)-1,9-dihydro-6H-purine-6-one 

Relevant articles and documents

The Reaction of 9-(2',3'-Dideoxy-β-D-glycero-pent-2-Enofuranosyl)-adenine Derivatives with Arene- and Alkenesulfenyl Chlorides. An Unusual Ring Opening Reaction of Thiiranium Ions

A series of arenesulfenyl chlorides and methanesulfenyl chloride were reacted in pyridine solution with 6-N-dibenzoyl-9-(2',3'-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine (1b).In each case, the relative abundance of isomeric β-chloroarene/alkene sulfides was estimated and used to assess the relative thermodynamic stabilities of the lyxo and ribo thiiranium ion intermediates and their steric susceptibilities to attack by nucleophile (Cl-).Subsequently, the β-chloroarene/alkene sulfides 8a-d to 13 a-d, upon alkaline treatment, underwent an unprecedented ylide-mediated β elimination of the intermediary lyxo and ribo thiiranium ions, to give only 2'-ene-thiol ethers 14-19.