108197-89-3Relevant academic research and scientific papers
Possible Pregnancy Interceptive Agents: Syntheses of 6,7-Dimethoxy-2,3,4-trisubstituted-quinolines and 3-Cyano-6,7-dimethoxy-2,4-disubstituted-1,4-dihydroquinolines
Neelima,Bhat, Balkrishen,Bhaduri, A. P.,Mehrotra, P. K.,Kamboj, V. P.
, p. 939 - 944 (2007/10/02)
Grignard reactions of 3-cyano-6,7-dimethoxy-2-substituted-quinolines with alkyl- and aryl-magnesium halides have revealed the effect of substituents at position-2 of the quinoline ring and also the effect of the nature of Grignard reagent towards 1,2-, 1,4- and 1,2:1,4-additions reactions.The Grignard reaction products have been found to undergo aromatisation and other side reactions during column chromatography.
