1082041-34-6

Basic information

• Product Name: 5-Bromo-4-methyl-1H-indazole
• Synonyms: 5-Bromo-4-methyl-1H-indazole;1H-Indazole,5-broMo-4-Methyl-
• CAS NO: 1082041-34-6
• Molecular Formula: C₈H₇BrN₂
• Molecular Weight: 211.05858
• Product Categories: Building Blocks;Indazole
• Mol File: 1082041-34-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 344.623 °C at 760 mmHg
• Flash Point: 162.222 °C
• Appearance: /
• Density: 1.655 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.21±0.40(Predicted)
• CAS DataBase Reference: 5-Bromo-4-methyl-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-4-methyl-1H-indazole(1082041-34-6)
• EPA Substance Registry System: 5-Bromo-4-methyl-1H-indazole(1082041-34-6)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 1082041-34-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-methyl-1H-indazole is a chemical compound with the molecular formula C8H7BrN2. It is a heterocyclic compound with a five-membered ring containing two nitrogen atoms. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development for various applications. 5-Bromo-4-methyl-1H-indazole may also have potential applications in the field of organic synthesis and medicinal chemistry. As a highly reactive compound, it requires careful handling and storage, and should only be used by trained professionals in appropriate laboratory settings. Its precise properties and applications may vary based on its specific use and formulation.

Upstream product

• 540-80-7 tert.-butylnitrite 
• 22364-25-6 4-bromo-2,3-dimethylaniline 
• 87-59-2 2,3-Dimethylaniline 

Downstream Products

• 1442120-60-6 4-methyl-2-({1-[(5-phenyloxazol-2-yl)carbonyl]piperidin-4-yl}methyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-5-carboxamide 
• 1442120-59-3 4-methyl-N-(2,2,2-trifluoroethyl)-2-[(1-{4-[3-(trifluoromethyl)phenoxy]benzoyl}piperidin-4-yl)methyl]-2H-indazole-5-carboxamide 
• 1442120-58-2 2-({1-[4-(3-fluorophenoxy)benzoyl]piperidin-4-yl}methyl)-4-methyl-N-(2,2,2-trifluoroethyl)-2H-indazole-5-carboxamide 
• 1442120-57-1 2-({1-[4-(4-cyanophenoxy)benzoyl]piperidin-4-yl}methyl)-4-methyl-N-(2,2,2-trifluoroethyl)-2H-indazole-5-carboxamide 
• 1442120-56-0 4-methyl-2-({1-[(3-phenyl-1,2,4-oxadiazol-5-yl)carbonyl]piperidin-4-yl}methyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-5-carboxamide 

Relevant articles and documents

Diastereoselective Copper-Mediated Conjugate Addition of Functionalized Magnesiates for the Preparation of Bisaryl Nrf2 Activators

A two-step metal-halogen exchange and diastereoselective copper-mediated Michael addition onto a complex α,β-unsaturated system has been developed and applied toward the synthesis of bisaryl Nrf2 activators. Optimization of metal-halogen exchange using (n

OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

Oxadiazole substituted indazole derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptors are disclosed.