108239-14-1Relevant academic research and scientific papers
Efficient syntheses of some versatile 3,5-bifunctional pyrazole building blocks
Sachse, Anna,Penkova, Larysa,Noel, Gilles,Dechert, Sebastian,Varzatskii, Oleg A.,Fritsky, Igor O.,Meyer, Franc
, p. 800 - 806 (2008)
A series of convenient synthetic procedures are reported for pyrazole derivatives with carbonyl or ester groups in the 3- and 5-positions and variable substitution pattern at C4 and at the functional side arms. All compounds have been characterized by 1H and 13C NMR spectroscopy, elemental analyses, and mass spectrometry. In addition, the structures of several pyrazole derivatives have been determined by single crystal X-ray diffraction, which provides insight into the effect of functional side arms on the hydrogen-bonded supramolecular motifs of NH-pyrazoles. Georg Thieme Verlag Stuttgart.
