1082467-04-6Relevant academic research and scientific papers
Mn(III)-Mediated Radical Cyclization of o-Alkenyl Aromatic Isocyanides with Boronic Acids: Access to N-Unprotected 2-Aryl-3-cyanoindoles
Liu, Lu,Li, Lei,Wang, Xin,Sun, Ran,Zhou, Ming-Dong,Wang, He
, p. 5826 - 5830 (2021/08/18)
The synthesis of N-unprotected 2-aryl-3-cyanoindoles was realized via the Mn(III)-mediated radical cascade cyclization of o-alkenyl aromatic isocyanides with boronic acids. A possible mechanism involving a sequential intermolecular radical addition, intramolecular cyclization, and cleavage of the C-C bond under mild reaction conditions is proposed. Mechanism studies show that H2O or O2 might provide the oxygen source for the elimination of benzaldehyde.
A 3 - cyano indole synthetic method of the compound
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Paragraph 0010; 0011; 0012; 0013-0030; 0049-0051, (2017/08/25)
The invention discloses a method for synthesizing a 3-cyanoindole compound and belongs to the technical field of synthetic technology. The technical solution provided by the invention is characterized that the method for synthesizing the 3-cyanoindole com
Selective access to 3-cyano-1 H -indoles, 9 H -pyrimido[4,5- b ]indoles, or 9 H -Pyrido[2,3- b ]indoles through copper-catalyzed one-pot multicomponent cascade reactions
Li, Bin,Guo, Shenghai,Zhang, Ju,Zhang, Xinying,Fan, Xuesen
, p. 5444 - 5456 (2015/06/16)
Novel and selective synthetic approaches toward indole derivatives via copper-catalyzed one-pot multicomponent cascade reactions of 1-bromo-2-(2,2-dibromovinyl)benzenes with aldehydes and aqueous ammonia are presented. Intriguingly, the concentration of a
A flexible synthesis of indoles from ortho -substituted anilines: A direct synthesis of isocryptolepine
Kraus, George A.,Guo, Haitao,Kumar, Ganesh,Pollock Iii, Gerald,Carruthers, Heather,Chaudhary, Divya,Beasley, Jonathan
experimental part, p. 1386 - 1393 (2010/07/16)
The reaction of anilines bearing a benzylic activating group in the ortho position with aromatic aldehydes or α,β-unsaturated aldehydes results in an efficient synthetic route to substituted indoles. Georg Thieme Verlag Stuttgart · New York.
